Department of Medical Laboratory Technology, College of Health and Medical Technology, University of Hilla, Babylon, Iraq
Research
Cytokines and hormones in polycystic ovary syndrome: a biochemical study in Iraqi women
Author(s): Nadia Kamile Al-Mashta*, Suzan Hammed Uraibi, Athraa Imad Habeeb, Shaima M. Al Sabty and Saif M. Hassan
Background: In Polycystic Ovary Syndrome (PCOS), sex hormones exert a regulatory influence over ovarian follicular development and a number of other functions within the body. It has been postulated that cytokines may operate as putative local regulators in PCOS.
Methodology: The prospective research groups were divided into six categories according to Body Mass Index (BMI), with a total of 150 women enrolled in the study. The aim was to investigate the link between sex hormones and inflammation markers in women with different body types and without PCOS.
Results: The results of the study indicated a notable decline (p<0.05) in hormone levels in the non-PCOS groups when compared to the PCOS groups. The lowest levels of TNF-α, IL-6 and IL-8 were observed in the non-PCOS groups. The highest levels were observed .. Read More»