Department of Obstetrics and Gynecology, Tanta University, Tanta, Egypt
Research
Evaluation of the role of interleukin-4 with doppler studies in pregnancy induced hypertension and its relation to the fetal outcome
Author(s): Abdelghaffar S Dawood* and Naglaa Hussien
The link between interleukins (IL) and endothelial cell injury supposed to lead to hypertension. This may be due to the release of oxygen free radicals, which injures the endothelium. Many authors hitherto studied Doppler velocimetry as a predictive tool for the development of preeclampsia(PE). We here attempted to determine the relation of IL-4 with the development of PE using umbilical/uterine artery Doppler velocimetry. 80 pregnant women of 30-36 week gestation were divided into 3 groups. The first group (n=20) consisted of a control group: primigravidae and normotensives. The second group (n=30) consisted of women with mild PE. The third group (n=30) consisted of women with severe PE. Doppler FVW were measured for the umbilical and uterine arteries IL-4 level was also measured. A statistically significant increase was observed in IL-4 levels in mild and severe PE groups.. Read More»