Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq

Publications

• Research   
  The impact of toll-like receptor 4 gene polymorphism on therapeutic response to metformin at the crossroad type two diabetes mellitus patients
  Author(s): Muntadher Noaman Jasim* and Ahmed J. Mohammed
  
  Diabetes is a diverse and intricate metabolic illness defined by high levels of glucose in the blood due to either resistance to insulin, inadequate production of insulin, or both. Metformin is one of the initial oral hypoglycemic agents frequently prescribed. Toll-Like 4 Receptors (TLR4) are receptors located on the surface of cells. It triggers the body's natural immune responses to harmful microorganisms by initiating a series of biochemical reactions that activate kinases and transcription factors. Two significant non-synonymous Single Nucleotide Polymorphisms (SNPs) (rs4986790 and rs4986791) have been discovered in the coding region (exon 3) of the TLR4 gene. Methodology: This prospective cohort study included one hundred patients who were newly diagnosed with type 2 diabetes mellitus. The study was carried out at Al Diwaniyah.. Read More»
  

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