Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Research
Comparison between agonist trigger with HCG luteal phase supplementation vs. HCG trigger with progesterone luteal phase supplementation in antagonist controlled hyperstimulation cycle regarding clinical pregnancy rate
Author(s): Maii Nawara*, Alaa El Din El Guindy, Walid Hitler, Sherif Yehia and Laila Aly Farid
Objective: We compared agonist trigger and HCG luteal support vs. standard HCG trigger and progesterone luteal supplementation in antagonist controlled hyperstimulation cycle as regards to clinical pregnancy rate.
Patients and Methods: The study was conducted on 100 women undergoing IVF treatment. They were randomized through a computer-generated list into two groups. Group I (n=50): Standard protocol HCG trigger with progesterone luteal support, and Group II (n=50): New protocol agonist trigger with HCG luteal support.
Results: Group II, compared with Group I, showed non-significant higher pregnancy rate. Group II showed much better compliance from patients: this was considered owing to the progesterone injection being administered intramuscularly or subcutaneously.
Conclusion: .. Read More»