Department of Pathological Analysis, College of Science, University of Thi-Qar, Nasiriyah, Iraq
Research
Evaluation of immunological markers among women with recurrent abortion in Thi-Qar province
Author(s): Widyan Gataa Washel*, Hassan Raysan Mobarak and Hind Muzhir Mousa
Many women around the world suffer from recurrent miscarriages associated with immune disorders Leading to decreased maternal and fetal tolerance. Thus, this study designed to evaluate the levels of Antiphospholipid antibodies (APL IgG & IgM and TGF-β1 in patients' women with recurrent abortions by using Enzyme-Linked Immune Sorbent Assay (ELISA). The current study included 100 women blood samples with recurrent miscarriage and 50 blood samples from apparently healthy women as control group their ages ranged between 17- 45 years. The results of the statistical analysis showed a significant increase in the levels of IgM, IgG and TGF-β1 in patients with recurrent miscarriage compared to the control group. Furthermore, highly significant positive strong correlation between IgM and IgG APL antibodies, and non-significant weak positive correlation between TGF-&bet.. Read More»