Abstract
Author(s): MARTA ZASTAWNY ,MARIUSZ ZIMMER
Summary Introduction. Progesterone is a steroid hormone produced by corpus luteum until approx. 10th week of pregnancy. It is responsible for maintenance and development of early pregnancy. In the 8th week of pregnancy the function of corpus luteum is taken over by trophoblast and after the 10th week of pregnancy trophoblast is the main source of progesterone. The concentration of progesterone increases gradually until the end of pregnancy. The Aim. The aim of the study is to present pregnancy outcome, including condition of the newborns, in a group of pregnant women who received progesterone treatment during the first trimester of pregnancy. Material and methods. A total of 214 women were enrolled for the study. 114 pregnant women who received progesterone in early pregnancy (study group) and 100 pregnant women who received no treatment during pregnancy (control group). We compare the pregnancy outcome, including condition of the newborns across both groups. Results: We found no significant differences between the groups with regard to the incidence of preterm labor, Caesarean section or disorders in first neonatal examination of newborns. Conclusions. Progesterone treatment in the first trimester of pregnancy does not influence the method of delivery and does not impact the newborn’s state. Receiving progesterone in the early pregnancy does not increase the incidence of congenital abnormalities between newborns. Key words: progesterone; labor; newborn